Selenium Levels based on Various Menopause Complaints Assessed by Menopause-specific Quality of Life Questionnaire before and after Selenium Intervention

BACKGROUND: Menopausal symptoms can greatly affect a woman’s personal, social, and work life. Selenium functions as cofactor for glutathione peroxidase helps minimize oxidative damage through cellular metabolism in postmenopausal women when estradiol production decreases, antioxidant protection is lost therefore stress increased. AIM: The aim of the study was to evaluated effect selenium supplementation on levels based menopausal complaints assessed by menopause-specific quality life questionnaire (MENQOL). MATERIALS AND METHODS: This research an analytical with quasi-experimental pre-test post-test one group only design. conducted all Medan who were aged >51-years-old met inclusion exclusion criteria. subjects underwent blood tests assess serum levels. If data normally distributed, dependent T test will be used, while if not Wilcoxon used. analysis results stated significant p < 0.05. RESULTS: Mean before administration 93.20 ± 17.253 μg/L which increased 132.12 19.866 after administration. Comparison found = 0.000 (p 0.05), means there difference Besides that, no scores aspects vasomotor disorders 1.000 [p > 0.05]), psychosocial 0.090 physical 0.323 sexual 0.959 0.05]) between CONCLUSION: Total MENQOL vasomotor, psychosocial, physical, disturbances did show statistically changes tablets 100 mcg/day 7 days.